Tuba Of Charm is a treasure item in Munchkin.
Flavor Text Edit
"This melodious instrument captivates your foes, giving you +3 to Run Away. If you successfully escape combat, snag a face-down treasure on your way out."
Tuba Of Charm gives you +3 to Run Away, meaning you must roll a 2 or higher. In combination with something like Elf, it guarantees you an escape, and therefore a Treasure, as that is the Tuba's other ability. Even though it takes only 1 Hand, it is still Big, which means it could be better to use another Big item. It can be sold for 300 Gold.